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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTA1
All Species:
26.97
Human Site:
T280
Identified Species:
74.17
UniProt:
P68133
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P68133
NP_001091.1
377
42051
T280
S
A
G
I
H
E
T
T
Y
N
S
I
M
K
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P68035
377
42000
T280
S
A
G
I
H
E
T
T
Y
N
S
I
M
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506759
377
42004
T280
S
A
G
I
H
E
T
T
Y
N
S
I
M
K
C
Chicken
Gallus gallus
P68139
377
42033
T280
S
A
G
I
H
E
T
T
Y
N
S
I
M
K
C
Frog
Xenopus laevis
P10995
377
41970
A280
S
A
G
I
H
E
T
A
Y
N
S
I
M
K
C
Zebra Danio
Brachydanio rerio
NP_001002066
377
41986
T280
S
A
G
I
H
E
T
T
Y
N
S
I
M
K
C
Tiger Blowfish
Takifugu rubipres
P53480
377
41956
A280
S
A
G
I
H
E
T
A
Y
N
S
I
M
K
C
Fruit Fly
Dros. melanogaster
P10987
376
41803
T279
A
C
G
I
H
E
T
T
Y
N
S
I
M
K
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P10986
376
41759
S279
S
A
G
I
H
E
T
S
Y
N
S
I
M
K
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
98.9
N.A.
97.6
100
99.1
99.1
98.9
93.9
N.A.
94.1
N.A.
Protein Similarity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
99.7
100
99.7
100
99.7
96.5
N.A.
96.8
N.A.
P-Site Identity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
100
93.3
100
93.3
86.6
N.A.
93.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
N.A.
N.A.
N.A.
100
N.A.
100
100
93.3
100
93.3
93.3
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
89
0
0
0
0
0
23
0
0
0
0
0
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
100
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
100
0
0
0
0
0
0
0
100
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
89
0
0
0
0
0
0
12
0
0
100
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
100
67
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _